Human Inosine Triphosphate Py-rophosphatase, ITPA ELISA Kit

SKU: E2026Hu

Size:96 Tests-1 Kit

Background:Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.

Research_area:Signal Transduction

Applications:ELISA

Target_protein:ITPA

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.05ng/ml

Detection range:0.1-30ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:inosine triphosphate py-rophosphatase

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9BY32

MASS(Da):21,446

GeneID:3704

Synonyms:C20orf37;DEE35;dJ794I6.3;Inosine triphosphatase;Inosine triphosphate pyrophosphatase;ITPA;ITPase;My049;Non-canonical purine NTP pyrophosphatase;Non-standard purine NTP pyrophosphatase;NTPase;Nucleoside-triphosphate diphosphatase;Nucleoside-triphosphate pyrophosphatase;Putative oncogene protein hlc14-06-p

Gene names:ITPA

Standard solution:32ng/ml