Human Immediate Early Response Gene 5 Protein, IER5 ELISA Kit

SKU: E5453Hu

Size:96 Tests-1 Kit

Background:Plays a role as a transcription factor (PubMed: 22132193, PubMed: 25355627). Mediates positive transcriptional regulation of several chaperone genes during the heat shock response in a HSF1-dependent manner (PubMed: 25355627, PubMed: 25816751). Mediates negative transcriptional regulation of CDC25B expression (PubMed: 22132193). Plays a role in the dephosphorylation of the heat shock factor HSF1 and ribosomal protein S6 kinase (S6K) by the protein phosphatase PP2A (PubMed: 25816751, PubMed: 26496226). Involved in the regulation of cell proliferation and resistance to thermal stress (PubMed: 22132193, PubMed: 25355627, PubMed: 26496226). Involved in the cell cycle checkpoint and survival in response to ionizing radiation (PubMed: 19238419, PubMed: 22132193). Associates with chromatin to the CDC25B promoter (PubMed: 22132193).

Research_area:Signal Transduction

Applications:ELISA

Target_protein:IER5

Reactivity:Human

Assay type:Sandwich

Sensitivity:5.32ng/L

Detection range:10-2000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Immediate Early Response Gene 5 Protein

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q5VY09

MASS(Da):33,704

GeneID:51278

Synonyms:IER 5;IER5;Immediate early response gene 5 protein

Gene names:IER5

Standard solution:2400ng/L