Human IL-6R Alpha / IL 6 Receptor ELISA Kit PicoKine®

SKU: EK0777

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: IL6R

Specificity: Natural and recombinant human IL-6R alpha

Background: IL6R alpha (IL6RA) also known as CD126 or IL6R, is a type I cytokine receptor. The IL6 receptor is a protein complex consisting of a IL-6 receptor subunit (IL6R) and interleukin 6 signal transducer Glycoprotein 130. IL6R also denotes the human gene encoding this subunit. Alternatively spliced transcript variants encoding distinct isoforms have been reported. IL6R subunit is also shared by many other cytokines. Interleukin-6 receptor has been shown to interact with Interleukin 6 and Ciliary neurotrophic factor. Ligand binding did not appear to affect IL6R dimerization status. IL6R dimerization occurs both on the cell surface and in solution.

Immunogen: Expression system for standard: NS0; Immunogen sequence: L20-D358

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Reconstitution:

Reference:

Uniprot ID: P08887

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

Isotype:

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Gene ID: 3570

Protein Name: Interleukin-6 receptor subunit alpha

Gene Full Name: interleukin 6 receptor

Synonyms: CD126; gp80; IL 6 receptor subunit alpha; IL 6R 1; IL 6R alpha; IL 6R subunit alpha; IL 6RA; IL-6 R alpha; IL-6R; IL 6R; IL6RA; interleukin 6 receptor; Membrane glycoprotein 80