Human Homeobox Protein Nkx-2.1, NKX2-1 ELISA Kit

SKU: E3298Hu

Size:96 Tests-1 Kit

Background:Transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis. Forms a regulatory loop with GRHL2 that coordinates lung epithelial cell morphogenesis and differentiation. Activates the transcription of GNRHR and plays a role in enhancing the circadian oscillation of its gene expression. Represses the transcription of the circadian transcriptional repressor NR1D1 (By similarity).

Research_area:Others

Applications:ELISA

Target_protein:NKX2-1

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.043ng/ml

Detection range:0.1-40ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Homeobox Protein Nkx-2.1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P43699

MASS(Da):38,596

GeneID:7080

Synonyms:Homeobox protein NK-2 homolog A;Homeobox protein Nkx-2.1;NKX21;NKX2-1;T/EBP;Thyroid nuclear factor 1;Thyroid transcription factor 1;Thyroid-specific enhancer-binding protein;TTF-1;

Gene names:NKX2-1

Standard solution:48ng/ml