Human Histone Rna Hairpin-binding Protein, SLBP ELISA Kit

SKU: E5421Hu

Size:96 Tests-1 Kit

Background:RNA-binding protein involved in the histone pre-mRNA processing. Binds the stem-loop structure of replication-dependent histone pre-mRNAs and contributes to efficient 3'-end processing by stabilizing the complex between histone pre-mRNA and U7 small nuclear ribonucleoprotein (snRNP), via the histone downstream element (HDE). Plays an important role in targeting mature histone mRNA from the nucleus to the cytoplasm and to the translation machinery. Stabilizes mature histone mRNA and could be involved in cell-cycle regulation of histone gene expression. Involved in the mechanism by which growing oocytes accumulate histone proteins that support early embryogenesis. Binds to the 5' side of the stem-loop structure of histone pre-mRNAs.

Research_area:Epigenetics and Nuclear Signaling

Applications:ELISA

Target_protein:SLBP

Reactivity:Human

Assay type:Sandwich

Sensitivity:5.17ng/L

Detection range:10-2000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Histone RNA hairpin-binding protein

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q14493

MASS(Da):31,286

GeneID:7884

Synonyms:HBP;Histone RNA hairpin-binding protein;Histone stem-loop-binding protein;SLBP

Gene names:SLBP

Standard solution:2560ng/L