Human Growth Hormone Receptor, GHR ELISA Kit

SKU: E6481Hu

Size:96 Tests-1 Kit

Background:Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to the JAK2/STAT5 pathway (By similarity). The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling. Isoform 2 up-regulates the production of GHBP and acts as a negative inhibitor of GH signaling.

Research_area:Signal Transduction; Cell Biology; Cancer

Applications:ELISA

Target_protein:GHR

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.019ng/ml

Detection range:0.05-10ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Growth Hormone Receptor

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P10912

MASS(Da):71,500

GeneID:2690

Synonyms:GH receptor;GH-binding protein;GHBP;GHR;Growth hormone receptor;Growth hormone-binding protein;Serum-binding protein;Somatotropin receptor

Gene names:GHR

Standard solution:12.8ng/ml