Human Glutaminyl-peptide Cyclotransferase, QPCT ELISA Kit

SKU: E5341Hu

Size:96 Tests-1 Kit

Background:Responsible for the biosynthesis of pyroglutamyl Peptides. Has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue. Also catalyzes N-terminal pyroglutamate formation. In vitro, catalyzes pyroglutamate formation of N-terminally truncated form of APP amyloid-beta Peptides [Glu-3]-amyloid-beta. May be involved in the N-terminal pyroglutamate formation of several amyloid-related plaque-forming Peptides.

Research_area:Metabolism

Applications:ELISA

Target_protein:QPCT

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.046ng/ml

Detection range:0.1-40ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Glutaminyl-Peptide Cyclotransferase

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q16769

MASS(Da):40,877

GeneID:25797

Synonyms:Glutaminyl cyclase;Glutaminyl-peptide cyclotransferase;Glutaminyl-tRNA cyclotransferase;Glutamyl cyclase;QC;QPCT;sQC

Gene names:QPCT

Standard solution:48ng/ml