Human Glutamate oxaloacetate transaminase 1,GOT1 ELISA KIT

SKU: E3302Hu

Size:96 Tests-1 Kit

Background:Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-mercaptopyruvate sulfurtransferase (3MST). Hydrogen sulfide is an important synaptic modulator and neuroprotectant in the brain. {ECO:0000269|PubMed:16039064}.

Research_area:

Applications:ELISA

Target_protein:GOT1

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.26ng/mL

Detection range:0.5-200ng/mL

Sample type:Serum, plasma or other biological fluids

Full product name:Glutamate oxaloacetate transaminase 1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P17174

MASS(Da):46248

GeneID:2805

Synonyms:GOT1

Gene names:GOT1

Standard solution:240ng/mL