Human Glucagon Receptor, GCGR ELISA Kit

SKU: E5330Hu

Size:96 Tests-1 Kit

Background:G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Plays an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Promotes activation of adenylate cyclase. Besides, plays a role in signaling via a phosphatidylinositol-calcium second messenger system.

Research_area:Others

Applications:ELISA

Target_protein:GCGR

Reactivity:Human

Assay type:Sandwich

Sensitivity:10.14ng/L

Detection range:20-4500ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Glucagon Receptor

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P47871

MASS(Da):54,009

GeneID:2642

Synonyms:GCGR;GL-R;Glucagon receptor

Gene names:GCGR

Standard solution:4800ng/L