Human Galactoside 2-alpha-L-fucosyltransferase 2,FUT2 ELISA KIT

SKU: E4900Hu

Size:96 Tests-1 Kit

Background:Catalyzes the transfer of L-fucose, from a guanosine diphosphate-beta-L-fucose, to the terminal galactose on both O- and N-linked glycans chains of cell surface glycoproteins and glycolipids and the resulting epitope regulates several processes such as cell-cell interaction including host-microbe interaction, cell surface expression and cell proliferation (PubMed:7876235, PubMed:8018146, PubMed:12692541). Preferentially fucosylates gangliosides GA1 and GM1 in the antrum, cecum and colon and in the female reproductive organs (By similarity). Fucosylated host glycoproteins or glycolipids mediate interaction with intestinal microbiota influencing its composition (PubMed:22068912, PubMed:21625510, PubMed:24733310). Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen which is an essential substrate for the final step in the soluble ABO blood group antigen synthesis pathway (PubMed:7876235). {ECO:0000250|UniProtKB:Q9JL27, ECO:0000269|PubMed:12692541, ECO:0000269|PubMed:21625510, ECO:0000269|PubMed:22068912, ECO:0000269|PubMed:24733310, ECO:0000269|PubMed:7876235, ECO:0000269|PubMed:8018146}.

Research_area:

Applications:ELISA

Target_protein:FUT2

Reactivity:Human

Assay type:Sandwich

Sensitivity:1.55ng/ml

Detection range:3-900ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Galactoside 2-alpha-L-fucosyltransferase 2

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q10981

MASS(Da):39017

GeneID:2524

Synonyms:FUT2 SEC2

Gene names:FUT2

Standard solution:960ng/ml