Human Follistatin-related Protein 3, FSTL3 ELISA Kit

SKU: E1914Hu

Size:96 Tests-1 Kit

Background:Isoform 1 or the secreted form is a binding and antagonizing protein for members of the TGF-beta family, such us activin, BMP2 and MSTN. Inhibits activin A-, activin B-, BMP2- and MSDT-induced cellular signaling; more effective on activin A than on activin B. Involved in bone formation; inhibits osteoclast differentiationc. Involved in hematopoiesis; involved in differentiation of hemopoietic progenitor cells, increases hematopoietic cell adhesion to fibronectin and seems to contribute to the adhesion of hematopoietic precursor cells to the bone marrow stroma. Isoform 2 or the nuclear form is probably involved in transcriptional regulation via interaction with MLLT10.

Research_area:Signal Transduction

Applications:ELISA

Target_protein:FSTL3

Reactivity:Human

Assay type:Sandwich

Sensitivity:10.09ng/L

Detection range:20-4500ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Follistatin-Related Protein 3

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:O95633

MASS(Da):27,663

GeneID:10272

Synonyms:Follistatin-like protein 3;Follistatin-related gene protein;Follistatin-related protein 3;FSTL 3;FSTL3

Gene names:FSTL3

Standard solution:4800ng/L