Human Fibronectin, FN ELISA Kit

SKU: E2002Hu

Size:96 Tests-1 Kit

Background:Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin (PubMed: 3024962, PubMed: 3900070, PubMed: 3593230, PubMed: 7989369). Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape (PubMed: 3024962, PubMed: 3900070, PubMed: 3593230, PubMed: 7989369). Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization (By similarity). Participates in the regulation of type I collagen deposition by osteoblasts (By similarity). [Anastellin]: Binds fibronectin and induces fibril formation. This fibronectin polymer, named superfibronectin, exhibits enhanced adhesive properties. Both anastellin and superfibronectin inhibit tumor growth, angiogenesis and metastasis. Anastellin activates p38 MAPK and inhibits lysophospholipid signaling.

Research_area:Cardiovascular

Applications:ELISA

Target_protein:FN1

Reactivity:Human

Assay type:Sandwich

Sensitivity:1.02ng/ml

Detection range:2-600ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Fibronectin

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P02751

MASS(Da):272,320

GeneID:2335

Synonyms:Anastellin;CIG;Cold-insoluble globulin;Fibronectin;FN;FN 1;FN1;Ugl-Y1;Ugl-Y2;Ugl-Y3

Gene names:FN1

Standard solution:800ng/ml