Human Fermitin Family Homolog 3, FERMT3 ELISA Kit

SKU: E5281Hu

Size:96 Tests-1 Kit

Background:Plays a central role in cell adhesion in hematopoietic cells (PubMed: 19234463, PubMed: 26359933). Acts by activating the integrin beta-1-3 (ITGB1, ITGB2 and ITGB3) (By similarity). Required for integrin-mediated platelet adhesion and leukocyte adhesion to endothelial cells (PubMed: 19234460). Required for activation of integrin beta-2 (ITGB2) in polymorphonuclear granulocytes (PMNs) (By similarity). Isoform 2 may act as a repressor of NF-kappa-B and apoptosis.

Research_area:Immunology

Applications:ELISA

Target_protein:FERMT3

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.023ng/ml

Detection range:0.05-20ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Fermitin Family Homolog 3

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q86UX7

MASS(Da):75,953

GeneID:83706

Synonyms:Fermitin family homolog 3;FERMT 3;FERMT3;Kindlin-3;MIG2-like protein;Unc-112-related protein 2

Gene names:FERMT3

Standard solution:24ng/ml