Human Fatty Acid Binding Protein 5, FABP5 ELISA Kit

SKU: E1399Hu

Size:96 Tests-1 Kit

Background:Intracellular carrier for long-chain fatty acids and related active lipids, such as the endocannabinoid, that regulates the metabolism and actions of the ligands they bind. In addition to the cytosolic transport, selectively delivers specific fatty acids from the cytosol to the nucleus, wherein they activate nuclear receptors (PubMed: 22170058, PubMed: 21395585). Delivers retinoic acid to the nuclear receptor peroxisome proliferator-activated receptor delta; which promotes proliferation and survival. May also serve as a synaptic carrier of endocannabinoid at central synapses and thus controls retrograde endocannabinoid signaling. Modulates inflammation by regulating PTGES induction via NF-kappa-B activation, and prostaglandin E2 (PGE2) biosynthesis during inflammation (By similarity). May be involved in keratinocyte differentiation (PubMed: 8092987).

Research_area:Signal Transduction

Applications:ELISA

Target_protein:FABP5

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.091ng/ml

Detection range:0.2-60ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Fatty Acid Binding Protein 5

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q01469

MASS(Da):15,164

GeneID:2171

Synonyms:E-FABP;Epidermal-type fatty acid-binding protein;FABP 5;FABP5;Fatty acid-binding protein 5;Fatty acid-binding protein, epidermal;PA-FABP;Psoriasis-associated fatty acid-binding protein homolog

Gene names:FABP5

Standard solution:64ng/ml