Human Fatty-acid Amidehydrolase 1, FAAH ELISA Kit

SKU: E5280Hu

Size:96 Tests-1 Kit

Background:Catalyzes the hydrolysis of endogenous amidated lipids like the sleep-inducing lipid oleamide ((9Z)-octadecenamide), the endocannabinoid anandamide (N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine), as well as other fatty amides, to their corresponding fatty acids, thereby regulating the signaling functions of these molecules (PubMed: 9122178, PubMed: 17015445, PubMed: 19926788). Hydrolyzes polyunsaturated substrate anandamide preferentially as compared to monounsaturated substrates (PubMed: 9122178, PubMed: 17015445). It can also catalyze the hydrolysis of the endocannabinoid 2-arachidonoylglycerol (2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol) (PubMed: 21049984). FAAH cooperates with PM20D1 in the hydrolysis of amino acid-conjugated fatty acids such as N-fatty acyl glycine and N-fatty acyl-L-serine, thereby acting as a physiological regulator of specific subsets of intracellular, but not of extracellular, N-fatty acyl amino acids (By similarity).

Research_area:Metabolism

Applications:ELISA

Target_protein:FAAH

Reactivity:Human

Assay type:Sandwich

Sensitivity:9.46ng/L

Detection range:20-4500ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Fatty-Acid Amide Hydrolase 1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:O00519

MASS(Da):63,066

GeneID:2166

Synonyms:Anandamide amidohydrolase 1;FAAH;Fatty acid ester hydrolase;Fatty-acid amide hydrolase 1;Oleamide hydrolase 1

Gene names:FAAH

Standard solution:4800ng/L