Human Estradiol 17-beta-dehydrogenase 12,HSD17B12 ELISA KIT

SKU: E3330Hu

Size:96 Tests-1 Kit

Background:Catalyzes the second of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme has a 3-ketoacyl-CoA reductase activity, reducing 3-ketoacyl-CoA to 3-hydroxyacyl-CoA, within each cycle of fatty acid elongation. Thereby, it may participate in the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. May also catalyze the transformation of estrone (E1) into estradiol (E2) and play a role in estrogen formation. {ECO:0000269|PubMed:12482854, ECO:0000269|PubMed:16166196}.

Research_area:

Applications:ELISA

Target_protein:HSD17B12

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.054ng/mL

Detection range:0.1-40ng/mL

Sample type:Serum, plasma or other biological fluids

Full product name:Estradiol 17-beta-dehydrogenase 12

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q53GQ0

MASS(Da):34324

GeneID:51144

Synonyms:HSD17B12 SDR12C1

Gene names:HSD17B12

Standard solution:48ng/mL