Human ESM1/Endocan ELISA Kit PicoKine®

SKU: EK0752

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: ESM1

Specificity: Natural and recombinant human ESM1

Background: Endothelial cell-specific molecule 1, also known as Endocan, is a protein that in humans is encoded by the ESM1 gene. This gene encodes a secreted protein which is mainly expressed in the endothelial cells in human lung and kidney tissues. The expression of this gene is regulated by cytokines, suggesting that it may play a role in endothelium-dependent pathological disorders. The transcript contains multiple polyadenylation and mRNA instability signals. ESM1 has been described as a specific biomarker of tip cells during neoangiogenesis by independent teams. Its expression has been shown to be increase in presence of pro-angiogenic growth factors such as VEGF (vascular endothelial growth factor) or FGF-2 (fibroblast growth factor 2).

Immunogen: Expression system for standard: NS0; Immunogen sequence: W20-R184

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Reference:

Uniprot ID: Q9NQ30

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 11082

Protein Name: Endothelial cell-specific molecule 1

Gene Full Name: endothelial cell specific molecule 1

Synonyms: Endothelial cell-specific molecule 1; ESM-1; ESM1