Human Ephrin B1, EFNB1 ELISA Kit

SKU: E6628Hu

Size:96 Tests-1 Kit

Background:Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development (PubMed: 8070404, PubMed: 7973638). Binding to Eph receptors residing on adjacent cells leads to contact-dependent bidirectional signaling into neighboring cells (PubMed: 8070404, PubMed: 7973638). Shows high affinity for the receptor tyrosine kinase EPHB1/ELK (PubMed: 8070404, PubMed: 7973638). Can also bind EPHB2 and EPHB3 (PubMed: 8070404). Binds to, and induces collapse of, commissural axons/growth cones in vitro (By similarity). May play a role in constraining the orientation of longitudinally projecting axons (By similarity).

Research_area:Others

Applications:ELISA

Target_protein:EFNB1

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.031ng/ml

Detection range:0.05-30ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Ephrin B1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P98172

MASS(Da):38,007

GeneID:1947

Synonyms:EFL-3;EFNB 1;EFNB1;ELK ligand;ELK-L;EPH-related receptor tyrosine kinase ligand 2;Ephrin-B1;Ephrin-B1 C-terminal fragment;Ephrin-B1 CTF;Ephrin-B1 ICD;Ephrin-B1 intracellular domain;LERK-2

Gene names:EFNB1

Standard solution:32ng/ml