Human Endothelin ELISA Kit PicoKine®

SKU: EK0945

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: EDN1

Specificity: Natural and recombinant human Endothelin

Background: The endothelins is a family of structurally and pharmacologically distinct peptides, which has been identified and sequenced in humans. Three isoforms of human endothelin have been identified: endothelin-1, -2, and -3. Endothelin-1 is a potent, 21-amino acid vasoconstrictor peptide produced by vascular endothelial cells. Endothelins are 21-amino acid vasoconstricting peptides produced primarily in the endothelium having a key role in vascular homeostasis. Endothelins are implicated in vascular diseases of several organ systems, including the heart, general circulation and brain. Endothelins are proteins that constrict blood vessels and raise blood pressure. They are normally kept in balance by other mechanisms, but when they are over-expressed, they contribute to high blood pressure (hypertension) and heart disease.

Immunogen: A peptide reflecting the target protein in human. Sequence: C53-W73

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Reference:

Uniprot ID: P05305, P20800, P14138

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 1906, 1907, 1908

Protein Name:

Gene Full Name: endothelin 1, endothelin 2, endothelin 3

Synonyms: Big endothelin 1; ET1; HDLCQ7; PPET1; Preproendothelin 1; EDN2; EDN2_HUMAN; Endothelin 2; Endothelin-2; ET 2; ET-2; ET2; PPET2; Preproendothelin 2; Preproendothelin-2; EDN3; EDN3_HUMAN; Endothelin-3; ET 3; ET-3; PPET3; Preproendothelin 3; Preproendothelin-3