Human ECH1 ELISA Kit

SKU: E5175Hu

Size:96 Tests-1 Kit

Background:Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial is an enzyme that in humans is encoded by the ECH1 gene. This gene encodes a member of the hydratase/isomerase superfamily. The gene product shows high sequence similarity to enoyl-CoA hydratases of several species, particularly within a conserved domain characteristic of these proteins. The encoded protein, Δ3,5-Δ2,4-dienoyl-CoA isomerase, contains a C-terminal peroxisomal targeting sequence and localizes to peroxisomes. The rat ortholog, which localizes to the matrix of both the peroxisome and mitochondria, can isomerize 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA, indicating that it is a delta3,5-delta2,4-dienoyl-CoA isomerase. This enzyme functions in the auxiliary step of the fatty acid beta-oxidation pathway. Expression of the rat gene is induced by peroxisome proliferators.

Research_area:Tags & Cell Markers

Applications:ELISA

Target_protein:ECH1

Reactivity:Human

Assay type:Sandwich

Sensitivity:4.32ng/L

Detection range:10-2000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q96PE7

MASS(Da):18,749

GeneID:84693

Synonyms:DL-methylmalonyl-CoA racemase;ECH1;GLOD2;MCE;Methylmalonyl-CoA epimerase, mitochondrial

Gene names:MCEE

Standard solution:2400ng/L