Human Dickkopf-related Protein 2, DKK2 ELISA Kit

SKU: E5182Hu

Size:96 Tests-1 Kit

Background:Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity).

Research_area:Stem Cells

Applications:ELISA

Target_protein:DKK2

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.026ng/ml

Detection range:0.1-40ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Dickkopf-Related Protein 2

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9UBU2

MASS(Da):28,447

GeneID:27123

Synonyms:Dickkopf-2;Dickkopf-related protein 2;DKK 2;DKK2;Dkk-2;hDkk-2

Gene names:DKK2

Standard solution:48ng/ml