Human Dickkopf-4,DKK4 ELISA KIT

SKU: E2122Hu

Size:96 Tests-1 Kit

Background:Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity). {ECO:0000250}.

Research_area:

Applications:ELISA

Target_protein:DKK4

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.18ng/ml

Detection range:0.38-24ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Dickkopf-4

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9UBT3

MASS(Da):24876

GeneID:27121

Synonyms:DKK4

Gene names:DKK4

Standard solution:48ng/ml