Human Diacylglycerol kinase Alpha,DGKA ELISA KIT

SKU: E7428Hu

Size:96 Tests-1 Kit

Background:Diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids (PubMed:2175712, PubMed:15544348). Thereby, acts as a central switch between the signaling pathways activated by these second messengers with different cellular targets and opposite effects in numerous biological processes (PubMed:2175712, PubMed:15544348). Also plays an important role in the biosynthesis of complex lipids (Probable). Can also phosphorylate 1-alkyl-2-acylglycerol in vitro as efficiently as diacylglycerol provided it contains an arachidonoyl group (PubMed:15544348). Also involved in the production of alkyl-lysophosphatidic acid, another bioactive lipid, through the phosphorylation of 1-alkyl-2-acetyl glycerol (PubMed:22627129). {ECO:0000269|PubMed:15544348, ECO:0000269|PubMed:2175712, ECO:0000269|PubMed:22627129, ECO:0000305}.

Research_area:

Applications:ELISA

Target_protein:DGKA

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.088ng/ml

Detection range:0.2-70ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Diacylglycerol kinase Alpha

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P23743

MASS(Da):82630

GeneID:1606

Synonyms:DGKA DAGK DAGK1

Gene names:DGKA

Standard solution:80ng/ml