Human Decoy Receptor 3, DCR3 ELISA Kit

SKU: E4615Hu

Size:96 Tests-1 Kit

Background:Decoy receptor 3 (Dcr3), also known as tumor necrosis factor receptor superfamily member 6B (TNFRSF6B), TR6 and M68, is a soluble protein of the tumor necrosis factor receptor superfamily which inhibits Fas ligand-induced apoptosis. This gene belongs to the tumor necrosis factor receptor superfamily. It acts as a decoy receptor that competes with death receptors for ligand binding. The encoded protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death and T cell activation as well as to induce angiogenesis via neutralization of TL1A. Overexpression of this gene has been noted in various tumors e.g. gastrointestinal tract tumors, and it is located in a gene-rich cluster on chromosome 20, with other potentially tumor-related genes.

Research_area:Cell Biology

Applications:ELISA

Target_protein:DCR3

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.17ng/ml

Detection range:0.3-90ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Decoy Receptor 3

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q8NG85

MASS(Da):35,282

GeneID:391192

Synonyms:DCR3;Olfactory receptor 2L3

Gene names:OR2L3

Standard solution:96ng/ml