Human Cystathionine-gamma-lyase, CSE ELISA Kit

SKU: E0724Hu

Size:96 Tests-1 Kit

Background:Catalyzes the last step in the trans-sulfuration pathway from methionine to cysteine. Has broad substrate specificity. Converts cystathionine to cysteine, ammonia and 2-oxobutanoate. Converts two cysteine molecules to lanthionine and hydrogen sulfide. Can also accept homocysteine as substrate. Specificity depends on the levels of the endogenous substrates. Generates the endogenous signaling molecule hydrogen sulfide (H2S), and so contributes to the regulation of blood pressure. Acts as a cysteine-protein sulfhydrase by mediating sulfhydration of target proteins: sulfhydration consists of converting -SH groups into -SSH on specific cysteine residues of target proteins such as GAPDH, PTPN1 and NF-kappa-B subunit RELA, thereby regulating their function.

Research_area:Others

Applications:ELISA

Target_protein:CTH

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.12ng/ml

Detection range:0.2-60ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Cystathionine-Gamma-Lyase

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P32929

MASS(Da):44,508

GeneID:1491

Synonyms:CTH;Cystathionine gamma-lyase;Cysteine-protein sulfhydrase;Gamma-cystathionase

Gene names:CTH

Standard solution:80ng/ml