Human CILP ELISA Kit PicoKine®

SKU: EK1986

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: CILP

Specificity: Natural and recombinant human CILP

Background: Cartilage intermediate layer protein 1 is a protein that in humans is encoded by the CILP gene. It is mapped to 15q22.31. Major alterations in the composition of the cartilage extracellular matrix occur in joint disease, such as osteoarthrosis. This gene encodes the cartilage intermediate layer protein (CILP), which increases in early osteoarthrosis cartilage. The encoded protein was thought to encode a protein precursor for two different proteins; an N-terminal CILP and a C-terminal homolog of NTPPHase, however, later studies identified no nucleotide pyrophosphatase phosphodiesterase (NPP) activity. The full-length and the N-terminal domain of this protein was shown to function as an IGF-1 antagonist. An allelic variant of this gene has been associated with lumbar disc disease.

Immunogen: Expression system for standard: NS0; Immunogen sequence: M1-R720

Clonality:

Contents:

Purification:

Reconstitution:

Reference:

Uniprot ID: O75339

Host:

Concentration:

Conjugate:

Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

Isotype:

Phospho_site:

Clone Number:

Observed Molecular Weight:

Calculated Molecular Weight:

Gene ID: 8483

Protein Name: Cartilage intermediate layer protein 1

Gene Full Name: cartilage intermediate layer protein

Synonyms: Cartilage intermediate layer protein 1; CILP-1; Cartilage intermediate-layer protein; CILP; UNQ602/PRO1188