Human Chemerin/RARRES2 PicoKine® Quick ELISA Kit

SKU: FEK1329

Size: 96 wells/kit, with removable strips.

Storage: Store at 4°C for 6 months. (Ships with gel ice, can store for up to 3 days in room temperature. Refrigerate upon receipt.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: RARRES2

Specificity: Natural and recombinant Human RARRES2

Background: Chemerin, also known as RARRES2 or TIG2, is a protein that in humans is encoded by the RARRES2 gene. It is mapped to 7q36.1. Chemerin is a potent chemoattractant specific for antigen-presenting cells that requires proteolytic activation and acts as a ligand for the G protein-coupled receptor CMKLR1(also known as ChemR23). It is a 14 kDa protein secreted in an inactive form as prochemerin and is activated through cleavage of the C-terminus by inflammatory and coagulation serine proteases. Chemerin was found to stimulate chemotaxis of dendritic cells and macrophages to the site of inflammation. What’s more, the active protein has several roles, including that as an adipokine, and is truncated on both termini from the proprotein.

Immunogen: Expression system for standard: E.coli; Immunogen sequence: V17-S163

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Reference:

Uniprot ID: Q99969

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 5919

Protein Name: Retinoic acid receptor responder protein 2

Gene Full Name: retinoic acid receptor responder 2

Synonyms: Chemerin; HP10433; RAR responsive protein TIG2; RARRES2; TIG2