Human Cd209 Antigen, CD209 ELISA Kit

SKU: E5017Hu

Size:96 Tests-1 Kit

Background:DC-SIGN (Dendritic Cell-Specific Intercellular adhesion molecule-3-Grabbing Non-integrin) also known as CD209 (Cluster of Differentiation 209) is a protein which in humans is encoded by the CD209 gene. DC-SIGN is a C-type lectin receptor present on the surface of both macrophages and dendritic cells. DC-SIGN on macrophages recognises and binds with high affinity to high-mannose type N-glycans, a class of PAMPs (pathogen associated molecular patterns) commonly found on viruses, bacteria and fungi. This binding interaction activates phagocytosis. On myeloid and pre-plasmacytoid dendritic cells DC-SIGN mediates dendritic cell rolling interactions with blood endothelium and activation of CD4+ T cells, as well as recognition of pathogen haptens.

Research_area:Immunology

Applications:ELISA

Target_protein:CD209

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.13ng/mL

Detection range:0.3-90ng/mL

Sample type:Serum, plasma or other biological fluids

Full product name:CD209 antigen

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9NNX6

MASS(Da):45,775

GeneID:30835

Synonyms:CD antigen CD209;CD209;CD209 antigen;CDSIGN;CLEC4L;C-type lectin domain family 4 member L;DC-SIGN;DC-SIGN1;Dendritic cell-specific ICAM-3-grabbing non-integrin 1;hDC-SIGN

Gene names:CD209

Standard solution:96ng/mL