Human CCN1 PicoKine® Quick ELISA Kit

SKU: FEK1203

Size: 96 wells/kit, with removable strips.

Storage: Store at 4°C for 6 months. (Ships with gel ice, can store for up to 3 days in room temperature. Refrigerate upon receipt.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: CYR61

Specificity: Natural and recombinant human CYR61

Background: Cysteine-rich angiogenic inducer 61 (CYR61) or CCN family member 1 (CCN1), is a matricellular protein that in humans is encoded by the CYR61 gene. This gene is mapped to 1p22.3. CYR61 is capable of regulating a broad range of cellular activities, including cell adhesion, migration, proliferation, differentiation, apoptosis, and senescence through interaction with cell surface integrin receptors and heparan sulfate proteoglycans. During embryonic development, CYR61 is critical for cardiac septal morphogenesis, blood vessel formation in placenta, and vascular integrity. In adulthood CYR61 plays important roles in inflammation and tissue repair, and is associated with diseases related to chronic inflammation, including rheumatoid arthritis, atherosclerosis, diabetes-related nephropathy and retinopathy, and many different forms of cancers.

Immunogen: Expression system for standard: CHO; Immunogen sequence: A22-D381

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Uniprot ID: O00622

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 3491

Protein Name: CCN family member 1

Gene Full Name: cellular communication network factor 1

Synonyms: CCN family member 1; CCN1; CYR61; cysteine-rich protein 61; GIG1; IBP 10; IGF binding protein 10; IGFBP 10; IGFBP10; Protein CYR61; Protein GIG1