Human Carnosine dipeptidase 2,Cndp2 ELISA KIT

SKU: E7527Hu

Size:96 Tests-1 Kit

Background:Hydrolyzes a variety of dipeptides including L-carnosine but has a strong preference for Cys-Gly (PubMed:19346245). Acts as a functional tumor suppressor in gastric cancer via activation of the mitogen-activated protein kinase (MAPK) pathway. An elevated level of CNDP2 activates the p38 and JNK MAPK pathways to induce cell apoptosis, and a lower level of CNDP2 activates the ERK MAPK pathway to promote cell proliferation (PubMed:24395568). Isoform 2 may play a role as tumor suppressor in hepatocellular carcinoma (HCC) cells (PubMed:17121880). Catalyzes the production of N-lactoyl-amino acids from lactate and amino acids by reverse proteolysis (PubMed:25964343). {ECO:0000269|PubMed:17121880, ECO:0000269|PubMed:19346245, ECO:0000269|PubMed:24395568, ECO:0000269|PubMed:25964343}.

Research_area:

Applications:ELISA

Target_protein:CNDP2

Reactivity:Human

Assay type:Sandwich

Sensitivity:1.27ng/ml

Detection range:2.5-160ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q96KP4

MASS(Da):52878

GeneID:55748

Synonyms:CNDP2 CN2 CPGL HEL-S-13 PEPA

Gene names:CNDP2

Standard solution:320ng/ml