Human Caldesmon, CALD ELISA Kit

SKU: E1476Hu

Size:96 Tests-1 Kit

Background:Actin- and myosin-binding protein implicated in the regulation of actomyosin interactions in smooth muscle and nonmuscle cells (could act as a bridge between myosin and actin filaments). Stimulates actin binding of tropomyosin which increases the stabilization of actin filament structure. In muscle tissues, inhibits the actomyosin ATPase by binding to F-actin. This inhibition is attenuated by calcium-calmodulin and is potentiated by tropomyosin. Interacts with actin, myosin, two molecules of tropomyosin and with calmodulin. Also plays an essential role during cellular mitosis and receptor capping. Involved in Schwann cell migration during peripheral nerve regeneration (By similarity).

Research_area:Others

Applications:ELISA

Target_protein:CALD

Reactivity:Human

Assay type:Sandwich

Sensitivity:4.25ng/L

Detection range:8-1500ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Caldesmon

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q05682

MASS(Da):93,231

GeneID:800

Synonyms:CALD;Caldesmon;CDM;HCAD;H-CAD;LCAD;L-CAD;NAG22

Gene names:CALD1

Standard solution:3200ng/L