Human B-Cell CLL;Lymphoma 11A,Bcl11A;Ctip1 ELISA KIT

SKU: E6679Hu

Size:96 Tests-1 Kit

Background:Transcription factor (PubMed:16704730, PubMed:29606353). Associated with the BAF SWI/SNF chromatin remodeling complex (PubMed:23644491). Binds to the 5'-TGACCA-3' sequence motif in regulatory regions of target genes, including a distal promoter of the HBG1 hemoglobin subunit gamma-1 gene (PubMed:29606353). Involved in regulation of the developmental switch from gamma- to beta-globin, probably via direct repression of HBG1; hence indirectly repressing fetal hemoglobin (HbF) level (PubMed:29606353, PubMed:26375765). Involved in brain development (PubMed:27453576). May play a role in hematopoiesis (By similarity). Essential factor in lymphopoiesis required for B-cell formation in fetal liver (By similarity). May function as a modulator of the transcriptional repression activity of NR2F2 (By similarity). {ECO:0000250|UniProtKB:Q9QYE3, ECO:0000269|PubMed:16704730, ECO:0000269|PubMed:23644491, ECO:0000269|PubMed:29606353, ECO:0000303|PubMed:26375765, ECO:0000303|PubMed:27453576}.

Research_area:

Applications:ELISA

Target_protein:BCL11A

Reactivity:Human

Assay type:Sandwich

Sensitivity:3.55ng/L

Detection range:7-1500ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:B-Cell CLL;Lymphoma 11A

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9H165

MASS(Da):91197

GeneID:53335

Synonyms:BCL11A CTIP1 EVI9 KIAA1809 ZNF856

Gene names:BCL11A

Standard solution:1600ng/L