Human B-cell Antigen Receptor Complex-associated Protein Alpha Chain, CD79A ELISA Kit

SKU: E6672Hu

Size:96 Tests-1 Kit

Background:Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src-family tyrosine kinases. Represses BCR signaling during development of immature B-cells.

Research_area:Immunology; Cancer; Stem Cells

Applications:ELISA

Target_protein:CD79A

Reactivity:Human

Assay type:Sandwich

Sensitivity:9.99ng/L

Detection range:20-3800ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:B-cell antigen receptor complex-associated protein Alpha chain

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P11912

MASS(Da):25,038

GeneID:973

Synonyms:B-cell antigen receptor complex-associated protein alpha chain;CD antigen CD79a;CD79A;IGA;Ig-alpha;MB-1;MB-1 membrane glycoprotein;Membrane-bound immunoglobulin-associated protein;Surface IgM-associated protein;

Gene names:CD79A

Standard solution:4000ng/L