Human Anoctamin 6, ANO6 ELISA Kit

SKU: E2376Hu

Size:96 Tests-1 Kit

Background:Small-conductance calcium-activated nonselective cation (SCAN) Channel which acts as a regulator of phospholipid scrambling in platelets and osteoblasts. Phospholipid scrambling results in surface exposure of phosphatidylserine which in platelets is essential to trigger the clotting system whereas in osteoblasts is essential for the deposition of hydroxyapatite during bone mineralization. Has calcium-dependent phospholipid scramblase activity; scrambles phosphatidylserine, phosphatidylcholine and galactosylceramide (By similarity). Can generate outwardly rectifying chloride Channel currents in airway epithelial cells and Jurkat T lymphocytes.

Research_area:Cancer

Applications:ELISA

Target_protein:ANO6

Reactivity:Human

Assay type:Sandwich

Sensitivity:9.68ng/L

Detection range:20-7000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Anoctamin 6

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q4KMQ2

MASS(Da):106,165

GeneID:196527

Synonyms:ANO 6;ANO6;Anoctamin-6;SCAN Channel;Small-conductance calcium-activated nonselective cation Channel;Transmembrane protein 16F

Gene names:ANO6

Standard solution:8000ng/L