Human angiostatin,ANG ELISA KIT

SKU: E1210Hu

Size:96 Tests-1 Kit

Background:Binds to actin on the surface of endothelial cells; once bound, angiogenin is endocytosed and translocated to the nucleus. Stimulates ribosomal RNA synthesis including that containing the initiation site sequences of 45S rRNA. Cleaves tRNA within anticodon loops to produce tRNA-derived stress-induced fragments (tiRNAs) which inhibit protein synthesis and triggers the assembly of stress granules (SGs). Angiogenin induces vascularization of normal and malignant tissues. Angiogenic activity is regulated by interaction with RNH1 in vivo. {ECO:0000269|PubMed:12051708, ECO:0000269|PubMed:1400510, ECO:0000269|PubMed:19354288, ECO:0000269|PubMed:21855800}.

Research_area:

Applications:ELISA

Target_protein:ANG

Reactivity:Human

Assay type:Sandwich

Sensitivity:9.36ng/L

Detection range:20-4500ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:angiostatin

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P03950

MASS(Da):16550

GeneID:283

Synonyms:ANG RNASE5

Gene names:ANG

Standard solution:4800ng/L