Human Alpha-2-macroglobulin,A2M ELISA KIT

SKU: E1097Hu

Size:96 Tests-1 Kit

Background:Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region, a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase.

Research_area:

Applications:ELISA

Target_protein:A2M

Reactivity:Human

Assay type:Sandwich

Sensitivity:9.98ng/L

Detection range:20-4500ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P01023

MASS(Da):163291

GeneID:2

Synonyms:A2M CPAMD5 FWP007

Gene names:A2M

Standard solution:4800ng/L