GeneBio Systems
Human AGT/Serpin A8/Angiotensinogen ELISA Kit PicoKine®
Human AGT/Serpin A8/Angiotensinogen ELISA Kit PicoKine®
SKU:EK1465
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Size: 96 wells/kit, with removable strips.
Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
Form:
Reactivity: Human
Applications: ELISA
Application Details:
Gene Name: AGT
Specificity: Natural and recombinant human AGT
Background: AGT (ANGIOTENSINOGEN), also called SERPINA8, is an α-2-globulin that is produced constitutively and released into the circulation mainly by the liver. ATG is a member of the serpin family, although it is not known to inhibit other enzymes, unlike most serpins. Angiotensinogen is also known as renin substrate. The AGT gene is mapped on 1q42.2. And the human angiotensinogen gene contains 5 exons. The expression of AGT and enzymes required for its conversion to angiotensin II in human adipose tissue. Mutations in this AGT gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.
Immunogen: Expression system for standard: NS0; Immunogen sequence: D34-A485
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Reference:
Uniprot ID: P01019
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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.
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Gene ID: 183
Protein Name: Angiotensinogen
Gene Full Name: angiotensinogen
Synonyms: AGT; Ang I Angiotensin 2; Ang II Angiotensin 3; Ang III; Angiotensin; Angiotensin I; Angiotensin II; Angiotensin III; Angiotensinogen; ANHU; Des Asp[1] angiotensin II; Serpin A8; SERPINA8
