HSD17B8 Polyclonal Antibody

SKU: E-AB-15103

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: HSD17B8

Target Synonym: 17 beta HSD 8;17 beta hydroxysteroid dehydrogenase 8;17-beta-HSD 8;17-beta-hydroxysteroid dehydrogenase 8;17-beta-hydroxysteroid dehydrogenase VIII;3-oxoacyl-[acyl-carrier-protein] reductase;3-oxoacyl-acyl-carrier protein reductase;E. coli;homolog of;Beta ketoacyl [acyl carrier protein] reductase like;D6S2245E;DHB8;dJ1033B10.9;Estradiol 17 beta dehydrogenase 8;Estradiol 17-beta-dehydrogenase 8;Estrogen 17 oxidoreductase;FABG;FabG;E. coli;homolog of;FabG-like;FABGL;H2 KE6;H2-KE6;HKE6;HSD17B8;Hydroxysteroid (17 beta) dehydrogenase 8;Ke-6;KE6;KE6;mouse homolog of;Protein Ke6;Really interesting new gene 2 protein;RING2;SDR30C1;Short chain dehydrogenase/reductase family 30C member 1;Testosterone 17 beta dehydrogenase 8;Testosterone 17-beta-dehydrogenase 8

Research Areas: Neuroscience;Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat

Application: WB;IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: Q92506

Accession:

Background: In mice, the Ke6 protein is a 17-beta-hydroxysteroid dehydrogenase that can regulate the concentration of biologically active estrogens and androgens. It is preferentially an oxidative enzyme and inactivates estradiol, testosterone, and dihydrotestosterone. However, the enzyme has some reductive activity and can synthesize estradiol from estrone. The protein encoded by this gene is similar to Ke6 and is a member of the short-chain dehydrogenase superfamily. An alternatively spliced transcript of this gene has been detected, but the full-length nature of this variant has not been determined.

Concentration: 0.2 mg/mL

Immunogen: Recombinant protein of human HSD17B8

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: WB 1:500-1:2000;IHC 1:50-1:200

Calculated MW: 27kDa

ObservedMW: