HSD17B12 Antibody - Cat. #: CSB-PA687494LA01HU

SKU: CSB-PA687494LA01HU

Size :50ug

Clone Number:

Aliases:12,3-ketoacyl-CoA reductase,short chain antibody; 17 beta HSD 12 antibody; 17 beta hydroxysteroid dehydrogenase 12 antibody; 17-@beta-HSD XII antibody; 17-@beta-hydroxysteroid dehydrogenase XII antibody; 17-beta-HSD 12 antibody; 17-beta-hydroxysteroid dehydrogenase 12 antibody; 17beta HSD type 12 antibody; 3 ketoacyl CoA reductase antibody; 3-ketoacyl-CoA reductase antibody; DHB12_HUMAN antibody; Estradiol 17 beta dehydrogenase 12 antibody; Estradiol 17-beta-dehydrogenase 12 antibody; HSD17B12 antibody; Hydroxysteroid (17-beta) dehydrogenase 12 antibody; KAR antibody; KIK-I antibody; Kik1 antibody; SDR12C1 antibody; Short chain dehydrogenase/reductase family 12C member 1 antibody; Steroid dehydrogenase homolog antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q53GQ0

Immunogen:Recombinant Human Very-long-chain 3-oxoacyl-CoA reductase protein (40-181AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200, IF:1:50-1:200

Background:Catalyzes the second of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme has a 3-ketoacyl-CoA reductase activity, reducing 3-ketoacyl-CoA to 3-hydroxyacyl-CoA, within each cycle of fatty acid elongation. Thereby, it may participate to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. May also catalyze the transformation of estrone (E1) into estradiol (E2) and play a role in estrogen formation.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:HSD17B12

Research Areas:Cell biology; Metabolism; Signal transduction