HLA-E Polyclonal Antibody

SKU: E-AB-18997

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: HLA-E

Target Synonym: HLA class I histocompatibility antigen E alpha chain;EA1.2;EA2.1;HLA 6.2;HLA class I histocompatibility antigen alpha chain E;HLA class I histocompatibility antigen E alpha chain precursor ;HLA class I histocompatibility antigen E alpha chain precursor;HLA6.2;HLAE;Lymphocyte antigen;Major histocompatibility complex class I E;MHC;MHC class I antigen E;MHC HLA E alpha 1;MHC HLA E alpha 2.1;QA1

Research Areas: Cancer;Immunology

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human

Application: IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P13747

Accession:

Background: HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail.

Concentration: 0.9 mg/mL

Immunogen: Fusion protein of human HLA-E

Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method: Antigen affinity purification

Dilution: IHC 1:50-1:300

Calculated MW:

ObservedMW: