Histone H3 (Di Methyl Lys36) Monoclonal Antibody(1E6)

SKU: BT-MCA0696

Size:100μL

Background:Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails| instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.

Research_area:Epigenetics and nuclear signaling

Target_protein:HIST1H3A

applications:WB

Reactivity:Human,Mouse,Rat

Clonality:Monoclonal

Clone ID:

Host:Mouse

Isotype:IgG

Gene Symbol/ Name:Histone H3.2

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):15273

UniProt accession:Human: P68431; Q71DI3; P84243Q6LED0; P84245

Synonyms:H3K36ME2; HIST1H3A; H3FA; HIST1H3B; H3FL; HIST1H3C; H3FC; HIST1H3D; H3FB; HIST1H3E; H3FD; HIST1H3F; H3FI; HIST1H3G; H3FH; HIST1H3H; H3FK; HIST1H3I; H3FF; HIST1H3J; H3FJ; Histone H3.1; Histone H3; a; Histone H3; b; Histone H3; c; Histone H3; d; Histone H3; f; Histone H3; h; Histone H3; i; Histone H3; j; Histone H3; k; Histone H3; l; HIST2H3A; HIST2H3C; H3F2; H3FM; HIST2H3D; Histone H3.2; Histone H3; m; Histone H3; o; H3F3A; H3.3A; H3F3; PP781; H3F3B; H3.3B; Histone H3.3

GeneID:Human: 8350; 8351; 8352; 8353; 8354; 8355; 8356; 8357; 8358; 8968; Mouse: 319152; 15077; 15078; Rat: 291159; 100361558