Histone H2A.X Polyclonal Antibody

SKU: E-AB-70233

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:Histone H2A.X

Target Synonym:H2A histone family member X;H2A histone family member X;H2A.FX;H2A.X;H2a/x;H2AFX;H2AX;H2AX;Histone H2A.X

Research Areas:Cancer;Epigenetics and Nuclear Signaling

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB;IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:P16104,P27661

Accession:

Background:Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.

Concentration:0.86 mg/mL

Immunogen:KLH conjugated Synthetic peptide corresponding to Mouse Histone H2A.X

Buffer:PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

Purification method:Affinity purification

Dilution:WB 1:500-1:2000;IHC 1:300-1:800

Calculated MW:15-18kDa

ObservedMW:18kDa