HER-2 Monoclonal Antibody

SKU: BT-MCA4242

Size:100μL

Background:The C-erbB-2 (HER-2/neu) gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. Amplification or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors. High levels of c-erbB-2 were associated with estrogen receptor (ER) and progesterone receptor negativity. Overexpression of the c-erbB-2 oncogene has been shown to be associated with poor prognosis in ovarian and breast cance, The level of increased Neu expression can be a predictor of disease prognosis

Research_area:Others

Target_protein:HER-2

applications:IHC

Reactivity:Human

Clonality:Monoclonal

Clone ID:9B9D8

Host:Mouse

Isotype:Mouse IgG2b

Gene Symbol/ Name:HER-2

Immunogen:Purified recombinant fragment of HER-2 expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):

UniProt accession:P04626

Synonyms:HER-2, C-erB-2, erbB-2

GeneID:2064