HACE1 Antibody - Cat. #: CSB-PA223356

SKU: CSB-PA223356

Size :50ul

Clone Number:

Aliases:HACE1 antibody; KIAA1320E3 ubiquitin-protein ligase HACE1 antibody; EC 2.3.2.26 antibody; HECT domain and ankyrin repeat-containing E3 ubiquitin-protein ligase 1 antibody; HECT-type E3 ubiquitin transferase HACE1 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q8IYU2

Immunogen:Synthetic peptide of Human HACE1

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:100-1:200

Background:HACE1 (HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1), also known as KIAA1320, is a 909 amino acid protein that localizes to both the cytoplasm and the endoplasmic reticulum and contains one HECT domain and six ANK repeats. Expressed in kidney, heart and brain, HACE1 functions as an E3 ubiquitin-protein ligase that interacts with the proteasome and is thought to play a role in protein degradation. HACE1 is downregulated in Wilms tumor, suggesting a possible role in tumor suppression.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:HACE1

Research Areas:Epigenetics and Nuclear Signaling;Cancer;Cell biology