Gzma Antibody - Cat. #: CSB-PA010081LA01MO

SKU: CSB-PA010081LA01MO

Size :50ug

Clone Number:

Aliases:Gzma antibody; Ctla-3 antibody; Ctla3 antibody; Mtsp-1 antibody; Granzyme A antibody; EC 3.4.21.78 antibody; Autocrine thymic lymphoma granzyme-like serine protease antibody; CTLA-3 antibody; Fragmentin-1 antibody; T cell-specific serine protease 1 antibody; TSP-1 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Mus musculus (Mouse)

UniProt ID:P11032

Immunogen:Recombinant Mouse Granzyme A protein (29-260AA)

Raised in:Rabbit

Species Reactivity:Mouse, Human

Tested Applications:ELISA, WB; Recommended dilution: WB:1:500-1:5000

Background:Abundant protease in the cytosolic granules of cytotoxic T-cells and NK-cells which activates caspase-independent cell death with morphological features of apoptosis when delivered into the target cell through the immunological synapse. It cleaves after Lys or Arg. Cleaves APEX1 after \\\'Lys-31\\\' and destroys its oxidative repair activity. Cleaves the nucleosome assembly protein SET after \\\'Lys-189\\\', which disrupts its nucleosome assembly activity and allows the SET complex to translocate into the nucleus to nick and degrade the DNA (By similarity).

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:Gzma

Research Areas:Others