GTPase Kras Polyclonal Antibody

SKU: E-AB-40639

Size: 100μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: KRAS

Target Synonym: KRAS;KRAS2;RASK2;GTPase Kras;K-Ras 2;Ki-Ras;c-K-ras;c-Ki-ras;GTPase Kras

Research Areas: Cancer;Epigenetics and Nuclear Signaling;Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat

Application: WB

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P01116

Accession:

Background: KRAS,also called p21,is a member of the Ras superfamily of proteins. It is located on human chromosome 12,and contains four coding exons and a 5' non-coding exon (PMID: 12778136). KRAS is a membrane-anchored guanosine triphosphate/guanosine diphosphate (GTP/GDP)-binding protein and is widely expressed in most human cells. Like other members of the Ras family,the KRAS protein is a GTPase,and it is involved in intracellular signal transduction and mainly responsible for EGFR-signaling activation (PMID: 19117687). KRAS mutations have been found in various malignancies,including lung adenocarcinoma,mucinous adenoma,ductal carcinoma of the pancreas and colorectal carcinoma.

Concentration: 1 mg/mL

Immunogen: Recombinant Human KRAS protein expressed by E.coli.

Buffer: PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4

Purification method: Antigen Affinity Purification

Dilution: WB 1:1000-1:2000

Calculated MW: 21 kDa

ObservedMW: 21 kDa