GRIA2 Monoclonal Antibody

SKU: BT-MCA2305

Size:100μL

Background:Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, Gria1-4. The subunit encoded by this gene (Gria2) is subject to RNA editing (Q/R and R/G), which is thought to render the channels impermeable to Ca(2+), and to affect the kinetic aspects of these channels in rat brain. Alternative splicing, resulting in transcript variants encoding different isoforms (flip and flop), has been noted for this gene.

Research_area:Neuroscience

Target_protein:GRIA2

applications:WB, FCM

Reactivity:Human

Clonality:Monoclonal

Clone ID:7G6

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:GRIA2

Immunogen:Purified recombinant fragment of human GRIA2 (AA: 652-807) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):98.8kDa

UniProt accession:P42262

Synonyms:GluA2, GluR2, gluR-B, GluR-K2

GeneID:2891