GPER Polyclonal Antibody

SKU: BT-AP09587

Size:100μL

Background:This gene is a member of the G-protein coupled receptor 1 family and encodes a multi-pass membrane protein that localizes to the endoplasmic reticulum. The protein binds estrogen, resulting in intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus. This protein therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen. Alternate transcriptional splice variants which encode the same protein have been characterized.

Research_area:Epigenetics and nuclear signaling ; Metabolism; Neuroscience; Signal transduction

Target_protein:GPER

applications:WB, ELISA

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:G-protein coupled estrogen receptor 1

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: Q99527; Mouse: Q8BMP4; Rat: O08878

Synonyms:G-protein coupled estrogen receptor 1 ;Chemoattractant receptor-like 2;Flow-induced endothelial G-protein coupled receptor 1;FEG-1;G-protein coupled receptor 30;GPCR-BR;IL8-related receptor

GeneID:Human: 2852