GNL3L Antibody, FITC conjugated - Cat. #: CSB-PA865150LC01HU

SKU: CSB-PA865150LC01HU

Size :50ug

Clone Number:

Aliases:GNL3LGuanine nucleotide-binding protein-like 3-like protein antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9NVN8

Immunogen:Recombinant Human Guanine nucleotide-binding protein-like 3-like protein (1-582AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:

Background:Stabilizes TERF1 telomeric association by preventing TERF1 recruitment by PML. Stabilizes TERF1 protein by preventing its ubiquitination and hence proteasomal degradation. Does so by interfering with TERF1-binding to FBXO4 E3 ubiquitin-protein ligase. Required for cell proliferation. By stabilizing TRF1 protein during mitosis, promotes metaphase-to-anaphase transition. Stabilizes MDM2 protein by preventing its ubiquitination, and hence proteasomal degradation. By acting on MDM2, may affect TP53 activity. Required for normal processing of ribosomal pre-rRNA. Binds GTP.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:FITC

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:GNL3L

Research Areas:Others