GLP Monoclonal Antibody

SKU: BT-MCA3168

Size:100μL

Background:Glucagon-like peptide-1 (GLP-1) is an incretin hormone secreted from enteroendocrine L cells in response to ingested nutrients. The closely related peptides glucagon-like peptide (GLP-1) and glucagon have opposing effects on blood glucose. GLP-1 induces glucose-dependent insulin secretion in the pancreas, while glucagon stimulates gluconeogenesis and glycogenolysis in the liver. Glucagon is processed from a large precursor, proglucagon, in a tissue-specific manner in pancreatic alpha-cells. The identification of a hybrid peptide acting as both a GLP-1 agonist and a glucagon antagonist would provide a novel approach for the treatment of type 2 diabetes.

Research_area:Others

Target_protein:GLP

applications:

Reactivity:Human

Clonality:Monoclonal

Clone ID:1B7B4

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:GLP

Immunogen:Purified recombinant fragment of GLP expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):

UniProt accession:Q9H9B1

Synonyms:GLP

GeneID:79813